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Third Session
Moderator: James R. Kasser, MD
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Thesis Presenter: Robert K. Fullick, MD
Topic: Analysis of Three Non-operative Treatment Arms for Conservative Management of Stable Juvenile Osteochondritis Dissecans Lesions of the Knee
Discussant: Dennis Kramer, MD
Advisor: Mininder Kocher, MD
Dr. Robert Fullick investigated three conservative treatments for juvenile
osteochondritis dissecans (OCD) lesions of the knee. He noted that there
is little consensus regarding the optimal non-operative treatment of this
pathology. Dr. Fullick conducted a retrospective study examining 103 skeletally
immature patients (112 knees) who presented with a stable OCD lesion
of the knee. Patients were treated conservatively with 1) physical therapy and
activity modification, 2) unloader bracing and physical therapy, or 3) casting
followed by physical therapy. He found that overall 62.5% (70 lesions) were
considered healed after conservative treatment. Healing occurred in twentytwo
(59.5%) of thirty-seven lesions treated with physical therapy and activity
modification, thirty-two (71%) of forty-five lesions treated with unloader
bracing and physical therapy, and sixteen (53%) of thirty lesions treated with
casting. Dr. Fullick found no significant difference in healing rates between
treatment groups, however bracing plus physical therapy showed a trend
towards improved healing rates. Bivariate analysis demonstrated that younger
age, smaller lesion size, and shorter duration of symptoms at presentation
were significantly predictive of successful conservative treatment. He found
that less than two-thirds of stable knee OCD lesions healed when treated conservatively.
Dr. Fullick concluded that while there is no significant difference
in healing rates between the three types of conservative treatment examined,
patients treated with bracing plus physical therapy showed a trend towards
improved healing rates. Dr. Kramer commented that this study demonstrates
the power of collaboration between Boston and Philadelphia.
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Thesis Presenter: John Y. Kwon, MD
Topic: Correlating Injury Mechanism with Fracture Patterns of the Ankle: A Challenge to Lauge-Hansen and a Novel Technique for Studying Mechanisms of Injury Using Video Analysis from Youtube.com
Discussant: Christopher P. Chiodo, MD
Advisor: E. Kenneth Rodriguez, MD, PhD
Dr. John Kwon described a novel technique for studying injury mechanisms
using in-vivo injury videos obtained from Youtube.com and presented
the results of a case series using this methodology as it pertains to ankle
fractures. His study inclusion criteria included 1) video demonstrating clear
visualization of the mechanism of injury including foot position and deforming
force, 2) candidates who sustained a fracture or dislocation, and 3) x-rays
of adequate quality revealing a fracture of the ankle. Four reviewers classified
each video. After the videos and radiographs were independently classified
according to the Lauge-Hansen fracture classification, each participants
video and radiograph was examined together for correlation between mechanism
of injury and expected fracture pattern. 15 videos with corresponding
radiographs were reviewed. Eight had supination/adduction (SAD) deforming
trauma, and seven had pronation/external rotation (PER) deforming trauma
as appreciated in the videos. Injuries occurred as the result of skateboarding
(n=8), bicycling (n=2), wrestling (n=2), martial arts (n=2) and trampoline
injury (n=1). One study participant demonstrated a likely subtalar dislocation
with an SAD mechanism of injury but without fracture or dislocation.
When assessing ankle fractures, all five fractures judged by video to be SAD
injuries resulted in corresponding SAD pattern radiographic ankle fractures.
Of the seven fractures judged by video to be PER injuries, only two resulted in
PER pattern radiographic ankle fractures. Five PER injuries resulted in supination/
external rotation (SER) ankle fracture patterns. Dr. Kwon concluded
that Lauge-Hansens mechanistic classification may not consistently produce
the radiographic fracture pattern predicted for a given injury mechanism in
actual patients sustaining live injuries. He has also developed a flexible and
valuable methodology for studying injury mechanisms, one with a wide array
of potential future applications. Future direction includes continued recruitment
to statistically assess the validity of the Lauge-Hansen classification as
applied to in-vivo injuries and use of this methodology to study other injury
mechanisms. Dr. Chiodo applauded Dr. Kwons hard work and perseverance
in overcoming numerous obstacles to introduce a valuable new tool in the
study of orthopaedic trauma.
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Thesis Presenter: Babajide A. Ogunseinde, MD
Topic: Functional outcomes of staged (using external fixator) and unstaged AO/OTA type B and C distal tibia fractures at a level-1 trauma center
Discussant: Paul T. Appleton, MD
Advisor: E. Kenneth. Rodriguez, MD.
Dr. Babajide Ogunseinde presented a study comparing the functional
outcomes of staged and unstaged treatment of pilon fractures managed at a
level one trauma center. He noted that high-energy pilon fractures are complex
injuries requiring special consideration of soft tissue management and
timing of fixation. To study these complex injuries, Dr. Ogunseinde conducted
a retrospective cohort analysis of 72 patients treated for pilon fractures
between 2004 and 2008 and examined rate of complication, nonunion, infection,
and revision surgery. Average follow-up was 22 months (range 12-42
months). Fifty-one (70%) of the seventy-two patients underwent staged
treatment with an external fixator. Average healing time for all patients
regardless of treatment modality was 5.2 months. Healing time was highest
for AO/OTA C3 fractures (6.4 months) and lowest with staged AO/OTA type
B2/3 fractures (4.0) months. He found six nonunions in the staged group,
three of which were open fractures at presentation. All nonunions required
revision surgery with bone grafting, and all subsequently went on to union.
Fifteen patients had delayed union, defined as fracture healing greater than
six months. The visual analog scale (VAS) score rating pain was similar for
both unstaged and staged groups. There was a trend towards higher rate of
infection in the unstaged group which did not reach statistical significance.
However, when deep infections were isolated, there was a statistically significantly
increased rate of deep infections in the unstaged group. There were
no differences between groups when comparing satisfaction with treatment.
Dr. Ogunseinde concluded that both staged and unstaged treatment of pilon
fractures results in good functional outcomes but with a higher rate of deep
infection in the unstaged group.
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